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Eye Applicators

1. Ruthenium - 106 Eye Plaques

2. Accessories

3. Plaque Simulator Software

4, Iodine-125 Ophthalmic Seeds and COMS Ophthalmic Applicators

 

Ruthenium - 106 Eye Plaques



Ocular tumours have been treated with plaques or applicators since the 1960‘s. Lommatzsch & Vollmar introduced the use of Ruthenium-106/Rhodium-106 eye plaques in 1966. These plaques consist of a thin silver foil embedded with Ru-106. Ru-106 is a beta emitter with a maximum energy of 3.54 MeV. The half value time is 368.2 days.


Schematic Drawing of a Ru-106 Eye Plaque

Ruthenium - 106 Ophthalmic Applicators Factsheet ( pdf )


A total of 16 different variations of type and size are currently being offered. The plaque type is dependent on the indication for use. All plaques are 1mm in thickness and may be sewn onto the sclera using the eyelets around the perimeter. The surface dose rate of all models is 120 mGy/min. with an activity ranging from 10 to 50 MBq (0.3–1.4 mCi). The plaque remains on the eye for several days during which the patient is hospitalized.

 

Eye Applicator Accessories

Dummies
To minimize radiation exposure to the operator we recommend the use of dummies which are available for all plaques. The positioning of the plaque on the eye may be facilitated using the PMMA dummies. The eye is diaphanoscopically illuminated, while the dummy is positioned on the eye. The shadow of the tumour on the sclera allows optimal placement of the dummy. The dummy is then replaced with the radioactive plaque.

Diaphanoscope
For the positioning of the plaque we offer a high performance diaphanoscope with two different probes. The fibre optic stem is straight and allows to illuminate the inner eye via the pupil. The tumour can be visualized as a shadow on the sclera. The fibre optic probe is bent and creates a point of light. The projection of the periphery of the plaque or dummy can be visualized from the inner eye.

 
 

 

Plaque Simulator

Plaque Simulator is a 3D treatment simulation and modelling package for Ru-106, I-125, Pd-103 and Ir-192 plaque therapy of ocular tumours and macular degeneration. Applicable ophthalmic tumours include choroidal melanoma in adults, retinoblastoma in young children and various forms of metastatic disease.

Please note: Plaque Simulator is not medical software in the sense of, for example, FDA regulations, and therefore does not relieve physicians, physicists or dosimetrists from any of their dosimetric responsibilities or liabilities.

Detailed technical information and a demonstration version can be found on the Plaque Simulator Homepage.

Plaque Simulator Software Factsheet ( pdf )

Literature about dosimetry:
Astrahan M: A patch source model for treatment planning of ruthenium ophthalmic applicators. Med Phys. 30 (6), 2003, 1219-1228, info

Krintz A, et al: A Reanalysis of the Collaborative Ocular Melanoma Study Medium Tumor Trial Eye Plaque Dosimetry. I.J. Radiation Oncology, 56 (3), 2003, 889-898, info

Iodine-125 Ophthalmic Seeds and COMS Ophthalmic Applicators

IsoSeeds® I-125 for medical use are mostly applied for treatment of uveal melanoma, retinoblastoma, and other special applications.

Iodine-125 Ophthalmic Seeds ( pdf ) and COMS Ophthalmic Applicators ( pdf )
 

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Please contact Colin Walters at cwalters@seedos.com if you would like further  information or a quotation or you have questions

or comments about this web site.
SeeDOS Ltd, 26, The Maltings, Leighton Buzzard, Bedfordshire LU7 4BS, United Kingdom
Tel: +44 1525 850 670  • Fax: +44 1525 850 685
  

Please contact SeeDOS Ltd Enquiries at enquiries@seedos.com if you would like further product or service information, a quotation or you have questions

or comments about this web site.
SeeDOS Ltd, 26, The Maltings, Leighton Buzzard, Bedfordshire LU7 4BS, United Kingdom
Tel: +44 1525 850 670  • Fax: +44 1525 850 685


 

SeeDOS Ltd
Radiation Oncology Equipment and Services
Colin S Walters Copyright 2002
Last Modified : 02/12/10 12:52 PM